Start your run with Guardian Dove, Divine Hammer and the X Marks The Spot Artifacts.
Artifacts
Guardian DoveEach time you cast your spell, add an upgraded Intervention to hand.
Divine HammerIf you play an X cost card for 3 or more energy, Overcharge 1 and Zeal 2.
X Marks The SpotStart the run with one copy each of Aftershock, Hope and Say Your Prayers that can not be removed. For each time you play a non-X cost card, suffer 3 threat the following turn.
More X-cost cards will appear as card rewards.